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Quick Details

• ProName: Flurogestone Acetate CAS 2529-45-5
• CasNo: 2529-45-5
• Molecular Formula: C23H31FO5
• Appearance: crystallization
• Application: Clinically, it is mainly used as a pro...
• DeliveryTime: 3-5days
• PackAge: Barreled
• Port: shanghai
• ProductionCapacity: 5000 Metric Ton/Year
• Purity: 99%
• Storage: Refrigerator
• Transportation: 2-8°C
• LimitNum: 10 Kilogram
• Moisture Content: No
• Impurity: No
• Place of Origin: China

Superiority

Details

Physicochemical properties
Density: 1.2±0.1 g/cm3
Boiling point: 526.7±50.0 °C at 760 mmHg
Melting point: 267.5ºC
Molecular formula: C23H31FO5
Molecular weight: 406.488
Flash point: 272.3±30.1 °C
Exact quality: 406.215546
PSA: 80.67000
LogP: 1.93
Vapor pressure: 0.0±3.1 mmHg at 25°C
Refractive index: 1.548

Use
Fluprogesterone acetate is a pregnane substance. Odorless crystals. It is soluble in 2.5 parts of chloroform, 23 parts of ethanol, 100 parts of methanol, but hardly soluble in water. For biochemical research.

Preparation
The preparation method of fluoroprogesterone acetate takes 9a-fluorohydrocortisone as a raw material, dissolves it in an organic solvent, and reacts with acid chloride in the presence of an acid binding agent to obtain 9a fluoro-hydrocortisone-21-O- Esterify the Chemicalbook; then the ester is reacted with sodium iodide and sulfur-containing reducing agent in an organic solvent to de-esterify to synthesize fluoroprogesterone; finally, the fluoroprogesterone is reacted with acetyl chloride or acetic anhydride in an organic solvent , Synthesis of fluoroprogesterone acetate.